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Innate Immunity IM Reference . Primary is the first time a response occurs in the presence of an antigen while secondary refers to a response after the. This response will attack anything (specific immune response will only attack certain infections) that it comes in contact with. How Your Immune System Protects You From Infection Part 4 T lymphocytes GrassrootsHealth from www.grassrootshealth.net Innate, or nonspecific, immunity is the defense system with which you were born. Up to 24% cash back non specific immune response. Which is part of the nonspecific immune response apex?